TY  - JOUR
A1  - Wilke, Jan
A1  - Hollander, Karsten Peter
A1  - Mohr, Lisa
A1  - Edouard, Pascal
A1  - Fossati, Chiara
A1  - González-Gross, Marcela
A1  - Sánchez Ramírez, Celso
A1  - Laiño, Fernando
A1  - Tan, Benedict
A1  - Pillay, Julian David
A1  - Pigozzi, Fabio
A1  - Jimenez-Pavon, David
A1  - Sattler, Matteo C.
A1  - Jaunig, Johannes
A1  - Zhang, Mandy
A1  - Poppel, Mireille van
A1  - Heidt, Christoph
A1  - Willwacher, Steffen
A1  - Vogt, Lutz
A1  - Verhagen, Evert
A1  - Hespanhol, Luiz
A1  - Tenforde, Adam S.
T1  - Drastic reductions in mental well-being observed globally during the COVID-19 pandemic : results from the ASAP survey
T2  - Frontiers in medicine
N2  - Most countries affected by the COVID-19 pandemic have repeatedly restricted public life to control the contagion. However, the health impact of confinement measures is hitherto unclear. We performed a multinational survey investigating changes in mental and physical well-being (MWB/PWB) during the first wave of the pandemic. A total of 14,975 individuals from 14 countries provided valid responses. Compared to pre-restrictions, MWB, as measured by the WHO-5 questionnaire, decreased considerably during restrictions (68.1 ± 16.9 to 51.9 ± 21.0 points). Whereas 14.2% of the participants met the cutoff for depression screening pre-restrictions, this share tripled to 45.2% during restrictions. Factors associated with clinically relevant decreases in MWB were female sex (odds ratio/OR = 1.20, 95% CI: 1.11–1.29), high physical activity levels pre-restrictions (OR = 1.29, 95% CI 1.16–1.42), decreased vigorous physical activity during restrictions (OR = 1.14, 95% CI: 1.05–1.23), and working (partially) outside the home vs. working remotely (OR = 1.29, 95% CI: 1.16–1.44/OR = 1.35, 95% CI: 1.23–1.47). Reductions, although smaller, were also seen for PWB. Scores in the SF-36 bodily pain subscale decreased from 85.8 ± 18.7% pre-restrictions to 81.3 ± 21.9% during restrictions. Clinically relevant decrements of PWB were associated with female sex (OR = 1.62, 95% CI: 1.50–1.75), high levels of public life restrictions (OR = 1.26, 95% CI: 1.18–1.36), and young age (OR = 1.10, 95% CI: 1.03–1.19). Study findings suggest lockdowns instituted during the COVID-19 pandemic may have had substantial adverse public health effects. The development of interventions mitigating losses in MWB and PWB is, thus, paramount when preparing for forthcoming waves of COVID-19 or future public life restrictions.
KW  - coronavirus
KW  - WHO-5
KW  - SF-36
KW  - psychological health
KW  - pain
KW  - lockdowns
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/61088
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-610888
SN  - 2296-858X
VL  - 8
IS  - art. 578959
SP  - 1
EP  - 6
PB  - Frontiers Media
CY  - Lausanne
ER  -