TY - JOUR A1 - Dietrich, Helge M. A1 - Kremp, Florian A1 - Öppinger, Christian Manfred A1 - Ribaric, Luna A1 - Müller, Volker T1 - Biochemistry of methanol-dependent acetogenesis in Eubacterium callanderi KIST612 T2 - Environmental microbiology N2 - Methanol is the simplest of all alcohols, is universally distributed in anoxic sediments as a result of plant material decomposition and is constantly attracting attention as an interesting substrate for anaerobes like acetogens that can convert bio-renewable methanol into value-added chemicals. A major drawback in the development of environmentally friendly but economically attractive biotechnological processes is the present lack of information on biochemistry and bioenergetics during methanol conversion in these bacteria. The mesophilic acetogen Eubacterium callanderi KIST612 is naturally able to consume methanol and produce acetate as well as butyrate. To grasp the full potential of methanol-based production of chemicals, we analysed the genes and enzymes involved in methanol conversion to acetate and identified the redox carriers involved. We will display a complete model for methanol-derived acetogenesis and butyrogenesis in Eubacterium callanderi KIST612, tracing the electron transfer routes and shed light on the bioenergetics during the process. Y1 - 2021 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/63920 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-639201 SN - 1462-2920 N1 - Financial support by the European Research Area Cofund on BioTechnologies (ERA CoBioTech; project BIOMETCHEM) is gratefully acknowledged. VL - 23 IS - 8 SP - 4505 EP - 4517 PB - Blackwell CY - Oxford [u.a.] ER -