TY  - INPR
A1  - Sass, Julian
A1  - Bartschke, Alexander
A1  - Lehne, Moritz
A1  - Essenwanger, Andrea
A1  - Rinaldi, Eugenia
A1  - Rudolph, Stefanie
A1  - Heitmann, Kai U.
A1  - Vehreschild, Jörg Janne
A1  - Kalle, Christof von
A1  - Thun, Sylvia
T1  - The German Corona Consensus Dataset (GECCO): a standardized dataset for COVID-19 research
T2  - medRxiv
N2  - Background: The current COVID-19 pandemic has led to a surge of research activity. While this research provides important insights, the multitude of studies results in an increasing segmentation of information. To ensure comparability across projects and institutions, standard datasets are needed. Here, we introduce the “German Corona Consensus Dataset” (GECCO), a uniform dataset that uses international terminologies and health IT standards to improve interoperability of COVID-19 data.
Methods: Based on previous work (e.g., the ISARIC-WHO COVID-19 case report form) and in coordination with experts from university hospitals, professional associations and research initiatives, data elements relevant for COVID-19 research were collected, prioritized and consolidated into a compact core dataset. The dataset was mapped to international terminologies, and the Fast Healthcare Interoperability Resources (FHIR) standard was used to define interoperable, machine-readable data formats.
Results: A core dataset consisting of 81 data elements with 281 response options was defined, including information about, for example, demography, anamnesis, symptoms, therapy, medications or laboratory values of COVID-19 patients. Data elements and response options were mapped to SNOMED CT, LOINC, UCUM, ICD-10-GM and ATC, and FHIR profiles for interoperable data exchange were defined.
Conclusion: GECCO provides a compact, interoperable dataset that can help to make COVID-19 research data more comparable across studies and institutions. The dataset will be further refined in the future by adding domain-specific extension modules for more specialized use cases.
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/73562
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-735628
IS  - 2020.07.27.20162636
ER  -