TY - JOUR A1 - Seeger-Zybok, Rebekka A1 - Klingelhöfer, Doris A1 - Groneberg, Jan David Alexander T1 - Global risk factor evaluation of obstructive sleep apnea in relation to research activity and socioeconomic factors T2 - International journal of environmental research and public health N2 - Obstructive Sleep Apnea is emerging as a global health epidemic, particularly due to the obesity pandemic. However, comprehensive prevalence data are still lacking and global OSA research has not yet been structurally evaluated. Using the latest comprehensive age/gender-specific BMI and obesity data, a global landscape estimating the risk/burden of OSA was created. Results were presented in relation to an in-depth analysis of OSA research and countries’ socioeconomic/scientific background. While the USA, Canada, and Japan are the highest publishing countries on OSA, Iceland, Greece, and Israel appeared at the forefront when relating the scientific output to socioeconomic parameters. Conversely, China, India, and Russia showed relatively low performances in these relations. Analysis of the estimated population at risk (EPR) of OSA showed the USA, China, India, and Brazil as the leading countries. Although the EPR and OSA research correlated strongly, major regional discrepancies between the estimated demand and actual research performances were identified, mainly in, but not limited to, developing nations. Our study highlights regional challenges/imbalances in the global activity on OSA and allows targeted measures to mitigate the burden of undiagnosed/untreated OSA. Furthermore, the inclusion of disadvantaged countries in international collaborations could stimulate local research efforts and provide valuable insights into the regional epidemiology of OSA. KW - OSA KW - public health KW - epidemiology KW - risk factor KW - bibliometrics KW - prevalence KW - obesity Y1 - 2020 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/56387 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-563878 SN - 1660-4601 N1 - © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). VL - 17 IS - art. 6785 SP - 1 EP - 15 PB - MDPI CY - Basel ER -