TY  - JOUR
A1  - Passweg, Jakob R.
A1  - Baldomero, Helen
A1  - Bader, Peter
A1  - Bonini, Chiara
A1  - Cesaro, Simone
A1  - Dreger, Peter
A1  - Duarte, Rafael F.
A1  - Dufour, Carlo
A1  - Falkenburg, J. H. Frederik
A1  - Farge-Bancel, Dominique
A1  - Gennery, Andrew
A1  - Kröger, Nicolaus
A1  - Lanza, Francesco
A1  - Nagler, Arnon
A1  - Sureda, Anna
A1  - Mohty, Mohamad
T1  - Hematopoietic SCT in Europe 2013 : recent trends in the use of alternative donors showing more haploidentical donors but fewer cord blood transplants
T2  - Bone marrow transplantation
N2  - A record number of 39 209 HSCT in 34 809 patients (14 950 allogeneic (43%) and 19 859 autologous (57%)) were reported by 658 centers in 48 countries to the 2013 survey. Trends include: more growth in allogeneic than in autologous HSCT, increasing use of sibling and unrelated donors and a pronounced increase in haploidentical family donors when compared with cord blood donors for those patients without a matched related or unrelated donor. Main indications were leukemias, 11 190 (32%; 96% allogeneic); lymphoid neoplasias, 19 958 (57%; 11% allogeneic); solid tumors, 1543 (4%; 4% allogeneic); and nonmalignant disorders, 1975 (6%; 91% allogeneic). In patients without a matched sibling or unrelated donor, alternative donors are used. Since 2010 there has been a marked increase of 96% in the number of transplants performed from haploidentical relatives (802 in 2010 to 1571 in 2013), whereas the number of unrelated cord blood transplants has slightly decreased (789 in 2010 to 666 in 2013). The use of donor type varies greatly throughout Europe.
Y1  - 2015
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/42216
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-422160
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387247
SN  - 0268-3369
SN  - 0951-3078
SN  - 1476-5365
N1  - This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/
VL  - 50
IS  - 4
SP  - 476
EP  - 482
PB  - Nature Publishing Group
CY  - London
ER  -