TY - JOUR A1 - Al Naimi, Ammar A1 - Mouzakiti, Niki A1 - Hondrich, Marie A1 - Louwen, Frank A1 - Bahlmann, Franz T1 - The B-mode sonographic evaluation of the post-caesarean uterine wall and its methodology: a study protocol T2 - The journal of obstetrics and gynaecology research N2 - Aim: The aim of this study is to utilize the niche measurement guidelines outlined by Jordans et al. in order to establish normal values and accurate description of caesarean section scars in a normal population. After defining the normal distribution, abnormal pregestational scar characteristics will be identified for predicting adverse pregnancy outcomes. Methods: This is a prospective observational multicenter clinical study where women with a history of only one caesarean section and yet open family planning are enrolled. The uterine length, cervical length, niche length, niche depth, niche width, residual myometrial thickness, endometrial thickness, scar to internal os distance, anterior myometrial thickness superior and inferior to the scar and the posterior myometrial thickness opposite the scar, superior and inferior to it are measured in a pregestational uterus. The lower uterine segment is measured over a length of 3 cm during subsequent pregnancy and followed up until delivery. Results: Data from 500 patients will yield normal distribution curves for all predefined measurements. Establishing a correlation between deviations from the normal measures and adverse events would be instrumental for counseling women regarding subsequent pregnancy and mode of delivery. Conclusion: This study will demonstrate the changes of the post-caesarean scar from a non-pregnant uterus until delivery and can confirm the importance of the scar characteristics in predicting pregnancy outcome. KW - caesarean scar KW - caesarean section KW - post-caesarean uterus KW - sonography KW - uterine wall Y1 - 2020 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62162 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-621621 SN - 1447-0756 N1 - This work was supported by the Dr. Senckenbergische Stiftung, Frankfurt am Main. VL - 46 IS - 12 SP - 2547 EP - 2551 PB - Wiley-Blackwell CY - Oxford ER -