TY - JOUR A1 - Canullo, Luigi A1 - Dehner, Jan Friedrich A1 - Penarrocha, David A1 - Checchi, Vittorio A1 - Mazzoni, Annalisa A1 - Breschi, Lorenzo T1 - Soft tissue response to titanium abutments with different surface treatment: preliminary histologic report of a randomized controlled trial T2 - BioMed research international N2 - The aim of this preliminary prospective RCT was to histologically evaluate peri-implant soft tissues around titanium abutments treated using different cleaning methods. Sixteen patients were randomized into three groups: laboratory customized abutments underwent Plasma of Argon treatment (Plasma Group), laboratory customized abutments underwent cleaning by steam (Steam Group), and abutments were used as they came from industry (Control Group). Seven days after the second surgery, soft tissues around abutments were harvested. Samples were histologically analyzed. Soft tissues surrounding Plasma Group abutments predominantly showed diffuse chronic infiltrate, almost no acute infiltrate, with presence of few polymorphonuclear neutrophil granulocytes, and a diffuse presence of collagenization bands. Similarly, in Steam Group, the histological analysis showed a high variability of inflammatory expression factors. Tissues harvested from Control Group showed presence of few neutrophil granulocytes, moderate presence of lymphocytes, and diffuse collagenization bands in some sections, while they showed absence of acute infiltrate in 40% of sections. However, no statistical difference was found among the tested groups for each parameter (p > 0.05). Within the limit of the present study, results showed no statistically significant difference concerning inflammation and healing tendency between test and control groups. Y1 - 2016 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/41293 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-412932 SN - 2314-6141 SN - 2314-6133 N1 - Copyright © 2016 Luigi Canullo et al. This is an open access article distributed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 2016 IS - Article ID 2952530 SP - 1 EP - 7 PB - Hindawi CY - New York [u. a.] ER -