TY  - JOUR
A1  - Fulda, Simone
A1  - Gorman, Adrienne M.
A1  - Hori, Osamu
A1  - Samali, Afshin
T1  - Cellular stress responses: cell survival and cell death
T2  - International journal of cell biology
N2  - Cells can respond to stress in various ways ranging from the activation of survival pathways to the initiation of cell death that eventually eliminates damaged cells. Whether cells mount a protective or destructive stress response depends to a large extent on the nature and duration of the stress as well as the cell type. Also, there is often the interplay between these responses that ultimately determines the fate of the stressed cell. The mechanism by which a cell dies (i.e., apoptosis, necrosis, pyroptosis, or autophagic cell death) depends on various exogenous factors as well as the cell's ability to handle the stress to which it is exposed. The implications of cellular stress responses to human physiology and diseases are manifold and will be discussed in this review in the context of some major world health issues such as diabetes, Parkinson's disease, myocardial infarction, and cancer.
Y1  - 2012
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/24363
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-243636
SN  - 1687-8884
SN  - 1687-8876
VL  - 2010
IS  - Article ID 214074
PB  - Hindawi
CY  - New York, NY
ER  -