TY  - JOUR
A1  - With, Katja de
A1  - Allerberger, Franz
A1  - Ammann, Steffen
A1  - Apfalter, Petra
A1  - Brodt, Hans-Reinhard
A1  - Eckmanns, Tim
A1  - Fellhauer, Matthias
A1  - Geiss, Heinrich K.
A1  - Janata, Oskar
A1  - Krause, Robert
A1  - Lemmen, Sebastian
A1  - Meyer, Elisabeth
A1  - Mittermayer, Helmut
A1  - Porsche, Ulla
A1  - Presterl, Elisabeth
A1  - Reuter, Stefan
A1  - Sinha, Bhanu
A1  - Strauß, Richard
A1  - Wechsler-Fördös, Agnes
A1  - Wenisch, Christoph
A1  - Kern, Winfried V.
T1  - Strategies to enhance rational use of antibiotics in hospital : a guideline by the German society for infectious diseases
T2  - Infection
N2  - Introduction: In the time of increasing resistance and paucity of new drug development there is a growing need for strategies to enhance rational use of antibiotics in German and Austrian hospitals. An evidence-based guideline on recommendations for implementation of antibiotic stewardship (ABS) programmes was developed by the German Society for Infectious Diseases in association with the following societies, associations and institutions: German Society of Hospital Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian Society for Infectious Diseases and Tropical Medicine, Austrian Society for Antimicrobial Chemotherapy, Robert Koch Institute.
Materials and methods: A structured literature research was performed in the databases EMBASE, BIOSIS, MEDLINE and The Cochrane Library from January 2006 to November 2010 with an update to April 2012 (MEDLINE and The Cochrane Library). The grading of recommendations in relation to their evidence is according to the AWMF Guidance Manual and Rules for Guideline Development.
Conclusion: The guideline provides the grounds for rational use of antibiotics in hospital to counteract antimicrobial resistance and to improve the quality of care of patients with infections by maximising clinical outcomes while minimising toxicity. Requirements for a successful implementation of ABS programmes as well as core and supplemental ABS strategies are outlined. The German version of the guideline was published by the German Association of the Scientific Medical Societies (AWMF) in December 2013.
KW  - Antibiotic stewardship
KW  - ABS
KW  - Guideline
KW  - Antimicrobial resistance
KW  - Quality of care
KW  - Rational use
Y1  - 2016
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43009
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-430091
UR  - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889644
SN  - 1439-0973
SN  - 0300-8126
N1  - © The Author(s) 2016. Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
VL  - 44
IS  - 3, Art. 885
SP  - 395
EP  - 439
PB  - Urban & Vogel ; Springer
CY  - München ; Berlin ; Heidelberg
ER  -