TY  - JOUR
A1  - Tanyildiz, Yasemin
A1  - Payne, Emily
A1  - Gerber, Tiemo
A1  - Seidman, Larissa
A1  - Heimann, Axel
A1  - Kempski, Oliver
A1  - Leithner, Doris
A1  - García Bardon, Andreas
A1  - Klöckner, Roman Trutz
A1  - Hahn, Felix
A1  - Keric, Naureen
A1  - Masomi-Bornwasser, Julia
A1  - Brockmann, Marc Alexander
A1  - Kirschner, Stefanie
T1  - In vitro testing of a funnel-shaped tip catheter model to decrease clot migration during mechanical thrombectomy
T2  - Scientific reports
N2  - One limitation of mechanical thrombectomy (MT) is clot migration during procedure. This might be caused by abruption of the trapped thrombus at the distal access catheter (DAC) tip during stent-retriever retraction due to the cylindrical shaped tip of the DAC. Aiming to solve this problem, this study evaluates the proof-of-concept of a new designed funnel-shaped tip, in an experimental in vitro setting. Two catheter models, one with a funnel-shaped tip and one with a cylindrical-shaped tip, were compared in an experimental setup. For MT a self-made vessel model and thrombi generated from pig’s blood were used. MT was performed 20 times for each device using two different stent-retrievers, 10 times respectively. For the funnel-shaped model: for both stent-retrievers (Trevo XP ProVue 3/20 mm; Trevo XP ProVue 4/20 mm) MT was successful at first pass in 9/10 (90%), respectively. For the cylindrical-shaped model: MT was successful at first pass in 5/10 (50%) with the smaller stent-retriever and in 6/10 (60%) with the larger stent-retriever. The experiments show a better recanalization rate for funnel-shaped tips, than for cylindrical-shaped tips. These results are indicating a good feasibility for this new approach, thus the development of a prototype catheter seems reasonable.
KW  - Stroke
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/52976
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-529769
SN  - 2045-2322
N1  - Open Access: This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
VL  - 10
IS  - 1, Art. 633
SP  - 1
EP  - 7
PB  - Macmillan Publishers Limited, part of Springer Nature
CY  - [London]
ER  -