TY  - JOUR
A1  - Bernatz, Simon
A1  - Mahmoudi, Scherwin
A1  - Martin, Simon S.
A1  - Burck, Iris
A1  - Vogl, Thomas J.
A1  - Ackermann, Jörg
A1  - Stöver, Timo
A1  - Balster, Sven
A1  - Gröger, Maximilian
T1  - Differences in mastoid and middle-ear cavity opacification in CT between intensive care patients and patients with acute mastoiditis requiring surgical treatment
T2  - European journal of radiology open
N2  - Purpose: To stratify differences in visual semantic and quantitative imaging features in intensive care patients with nonspecific mastoid effusions versus patients with acute mastoiditis (AM) requiring surgical treatment. Methods: We included 48 patients (male, 28; female, 20; mean age, 59.5 ± 18.1 years) with mastoid opacification (AM, n = 24; control, n = 24) who underwent clinically indicated cerebral CT between 12/2007 and 07/2018 in this retrospective study. Semantic features described the extend and asymmetry of mastoid and middle-ear cavity opacification and complications like erosive changes. Minimum, maximum and mean Hounsfield unit (HU) values were obtained as quantitative features. We analyzed the features employing univariate testing. Results: Compared to intensive care patients, AM patients revealed asymmetric mastoid or middle-ear cavity opacification (likelihood-ratio (LR) < 0.001). Applying a dedicated threshold of the extent of opacification, AM patients reached significance levels of LR = 0.042 and 0.002 for mastoid and middle-ear cavity opacification. AM cases showed higher maximum and mean HU values (p = 0.009, p = 0.024). Conclusions: We revealed that the extent and asymmetry of mastoid and middle-ear cavity opacification differs significantly between AM patients and intensive care patients. Multicenter research is needed to expand our cohort and possibly pave the way to build a non-invasive predictive model for AM in the future.
KW  - Mastoiditis
KW  - Intensive care units
KW  - Exudates and transudates
KW  - Feasibility studies
KW  - Cohort studies
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/61449
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-614495
SN  - 2352-0477
VL  - 8
IS  - art. 100365
SP  - 1
EP  - 7
PB  - Elsevier Science
CY  - Amsterdam [u.a.]
ER  -