TY  - JOUR
A1  - Rutz, Jochen
A1  - Janicová, Andrea
A1  - Woidacki, Katja
A1  - Chun, Felix
A1  - Blaheta, Roman A.
A1  - Relja, Borna
T1  - Curcumin - a viable agent for better bladder cancer treatment
T2  - International journal of molecular sciences
N2  - Although the therapeutic armamentarium for bladder cancer has considerably widened in the last few years, severe side effects and the development of resistance hamper long-term treatment success. Thus, patients turn to natural plant products as alternative or complementary therapeutic options. One of these is curcumin, the principal component of Curcuma longa that has shown chemopreventive effects in experimental cancer models. Clinical and preclinical studies point to its role as a chemosensitizer, and it has been shown to protect organs from toxicity induced by chemotherapy. These properties indicate that curcumin could hold promise as a candidate for additive cancer treatment. This review evaluates the relevance of curcumin as an integral part of therapy for bladder cancer.
KW  - curcumin
KW  - bladder cancer
KW  - chemoresistance
KW  - chemoprotection
KW  - bioavailability
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/55433
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-554335
SN  - 1422-0067
N1  - © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
VL  - 21
IS  - 11, art. 3761
SP  - 1
EP  - 20
PB  - MDPI
CY  - Basel
ER  -