TY - JOUR A1 - Chen, Chih-Hao A1 - Coyac, Benjamin R. A1 - Arioka, Masaki A1 - Leahy, Brian A1 - Tulu, U. Serdar A1 - Aghvami, Maziar A1 - Holst, Stefan A1 - Hoffmann, Waldemar A1 - Quarry, Antony A1 - Bahat, Oded A1 - Salmon, Benjamin A1 - Brunski, John A1 - Helms, Jill A. T1 - A novel osteotomy preparation technique to preserve implant site viability and enhance osteogenesis T2 - Journal of Clinical Medicine N2 - The preservation of bone viability at an osteotomy site is a critical variable for subsequent implant osseointegration. Recent biomechanical studies evaluating the consequences of site preparation led us to rethink the design of bone-cutting drills, especially those intended for implant site preparation. We present here a novel drill design that is designed to efficiently cut bone at a very low rotational velocity, obviating the need for irrigation as a coolant. The low-speed cutting produces little heat and, consequently, osteocyte viability is maintained. The lack of irrigation, coupled with the unique design of the cutting flutes, channels into the osteotomy autologous bone chips and osseous coagulum that have inherent osteogenic potential. Collectively, these features result in robust, new bone formation at rates significantly faster than those observed with conventional drilling protocols. These preclinical data have practical implications for the clinical preparation of osteotomies and alveolar bone reconstructive surgeries. KW - osteogenesis KW - osteotomy KW - bone healing KW - bone chips KW - drilling tool design Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/49085 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-490859 SN - 2077-0383 N1 - This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0). VL - 8 IS - 2, Art. 170 SP - 1 EP - 13 PB - MDPI CY - Basel ER -