TY  - JOUR
A1  - García Rosales, Francisco
A1  - López Jury, Luciana
A1  - González Palomares, Eugenia
A1  - Wetekam, Johannes
A1  - Cabral-Calderı́n, Yuranny
A1  - Kiai, Ava
A1  - Kössl, Manfred
A1  - Hechavarria-Cueria, Julio C.
T1  - Echolocation-related reversal of information flow in a cortical vocalization network
T2  - Nature Communications
N2  - The mammalian frontal and auditory cortices are important for vocal behavior. Here, using local-field potential recordings, we demonstrate that the timing and spatial patterns of oscillations in the fronto-auditory network of vocalizing bats (Carollia perspicillata) predict the purpose of vocalization: echolocation or communication. Transfer entropy analyses revealed predominant top-down (frontal-to-auditory cortex) information flow during spontaneous activity and pre-vocal periods. The dynamics of information flow depend on the behavioral role of the vocalization and on the timing relative to vocal onset. We observed the emergence of predominant bottom-up (auditory-to-frontal) information transfer during the post-vocal period specific to echolocation pulse emission, leading to self-directed acoustic feedback. Electrical stimulation of frontal areas selectively enhanced responses to sounds in auditory cortex. These results reveal unique changes in information flow across sensory and frontal cortices, potentially driven by the purpose of the vocalization in a highly vocal mammalian model.
KW  - Cortex
KW  - Neural circuits
KW  - Sensorimotor processing
KW  - Sensory processing
Y1  - 2022
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/69482
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-694829
SN  - 2041-1723
N1  - This work was supported by the DFG (Grant No. HE 7478/1‐1, to J.C.H.), and the Joachim-Herz Foundation (Fellowship granted to F.G.R.).
N1  - Open Access funding enabled and organized by Projekt DEAL.
VL  - 13
IS  - art. 3642
SP  - 1
EP  - 15
PB  - Nature Publishing Group UK
CY  - [London]
ER  -