TY - JOUR A1 - Brunkhorst-Kanaan, Nathalie A1 - Libutzki, Berit A1 - Reif, Andreas A1 - Larsson, Henrik A1 - McNeill, Rhiannon V. A1 - Kittel-Schneider, Sarah T1 - ADHD and accidents over the life span – A systematic review T2 - Neuroscience & biobehavioral reviews N2 - Studies have demonstrated an increased risk of accidents and injuries in children, adolescents and adults with attention-deficit/hyperactivity disorder (ADHD). However, little is known about how accident risk may alter over the lifespan. Additionally, it would be important to know if the most common types of accidents and injuries differ in ADHD patients over different age groups. Furthermore, there is increasing evidence of an ameliorating effect of ADHD medication on accident risk. Lastly, the underlying risk factors and causal mechanisms behind increased accident risk remain unclear. We therefore conducted a systematic review focusing on the above described research questions. Our results suggested that accident/injury type and overall risk changes in ADHD patients over the lifespan. ADHD medication appeared to be similarly effective at reducing accident risk in all age groups. However, studies with direct comparisons of accident/injuries and effects of medication at different age groups or in old age are still missing. Finally, comorbidities associated with ADHD such as substance abuse appear to further increase the accident/injury risk. KW - ADHD KW - Accidents KW - Injuries KW - Stimulant KW - Methylphenidate KW - Atomoxetine KW - Amphetamine KW - Trajectories Y1 - 2021 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/78095 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-780957 SN - 0149-7634 VL - 125 SP - 582 EP - 591 PB - Elsevier CY - Amsterdam ER -