TY  - JOUR
A1  - Köhrmann, Martin
A1  - Schellinger, Peter Dieter
A1  - Tsivgoulis, Georgios
A1  - Steiner, Thorsten
T1  - Patent foramen ovale : story closed?
T2  - Journal of stroke
N2  - The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials suggest a benefit with regard of preventing further ischemic strokes. With this discrepancy in results it is important to discuss recent trials in detail and evolve an informed clinical approach for daily practice.
KW  - Stroke
KW  - Foramen ovale
KW  - patent
KW  - Intracranial embolism
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/49082
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-490821
SN  - 2287-6391
SN  - 2287-6405
N1  - This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 21
IS  - 1
SP  - 23
EP  - 30
PB  - Korean Stroke Society
CY  - Seoul
ER  -