TY  - JOUR
A1  - Eckhardt, Thurid
A1  - Horst, Klemens
A1  - Störmann, Philipp
A1  - Bläsius, Felix Marius
A1  - Hofman, Martijn
A1  - Herren, Christian
A1  - Kobbe, Philipp
A1  - Hildebrand, Frank
A1  - Andruszkow, Hagen
T1  - Impact of chest trauma and overweight on mortality and outcome in severely injured patients
T2  - Journal of Clinical Medicine
N2  - The morbidity and mortality of severely injured patients are commonly affected by multiple factors. Especially, severe chest trauma has been shown to be a significant factor in considering outcome. Contemporaneously, weight-associated endocrinological, haematological, and metabolic deviations from the norm seem to have an impact on the posttraumatic course. Therefore, the aim of this study was to determine the influence of body weight on severely injured patients by emphasizing chest trauma. A total of 338 severely injured patients were included. Multivariate regression analyses were performed on patients with severe chest trauma (AIS ≥ 3) and patients with minor chest trauma (AIS < 3). The influence of body weight on in-hospital mortality was evaluated. Of all the patients, 70.4% were male, the median age was 52 years (IQR 36–68), the overall Injury Severity Score (ISS) was 24 points (IQR 17–29), and a median BMI of 25.1 points (IQR 23–28) was determined. In general, chest trauma was associated with prolonged ventilation, prolonged ICU treatment, and increased mortality. For overweight patients with severe chest trauma, an independent survival benefit was found (OR 0.158; p = 0.037). Overweight seems to have an impact on the mortality of severely injured patients with combined chest trauma. Potentially, a nutritive advantage or still-unknown immunological aspects in these patients affecting the intensive treatment course could be argued.
KW  - chest trauma
KW  - eight disorders
KW  - overweight
KW  - obesity
KW  - outcome
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/55198
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-551988
SN  - 2077-0383
VL  - 6
IS  - (9), art. 2752
PB  - MDPI
CY  - Basel
ER  -