TY  - JOUR
A1  - Pinter, Andreas
A1  - Thormann, Henrik
A1  - Angeletti, Flavia
A1  - Jalili, Ahmad
T1  - Calcipotriol/betamethasone dipropionate aerosol foam for the treatment of psoriasis vulgaris : case series and review of the literature
T2  - Clinical, cosmetic and investigational dermatology
N2  - An aerosol foam formulation of a once-daily, fixed-dose combination of a synthetic vitamin D3 analog/synthetic corticosteroid (calcipotriol [Cal] 50 µg/g and betamethasone dipropionate [BD] 0.5 mg/g) has recently been introduced for the topical treatment of plaque psoriasis in adults. Data from several sources – randomized controlled trials, case reports (as highlighted in this review), and real-world evidence (RWE) – underscore the considerable and rapid clinical response, effectiveness, and favorable safety and tolerability of Cal/BD aerosol foam in mild-to-moderate psoriatic patients previously treated with class 3 or 4 topical corticosteroids, in patients unsatisfied with ongoing phototherapy in combination with topical therapy and in patients with moderate-to-severe psoriasis. In addition, our case series, considered together with other RWE, highlights that Cal/BD aerosol foam is more effective and with greater levels of patient preference and acceptability than comparator preparations. Thus, Cal/BD aerosol foam offers several treatment advantages, including relief of itch, and is an appropriate first-line topical therapy for consideration in patients with psoriasis of any severity.
KW  - aerosol
KW  - betamethasone dipropionate
KW  - calcipotriol
KW  - psoriasis
Y1  - 2018
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/47733
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-477339
SN  - 1178-7015
N1  - This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.
VL  - 11
SP  - 451
EP  - 459
PB  - Dove Medical Press
CY  - Albany, Auckland
ER  -