TY  - JOUR
A1  - Waard, Antonius A. de
A1  - Verkerk, Tamara
A1  - Jongsma, Marlieke L. M.
A1  - Hoefakker, Kelly
A1  - Sethumadhavan, Sunesh
A1  - Gerke, Carolin
A1  - Bliss, Sophie
A1  - Kong, Xiangrui
A1  - Janssen, George M. C.
A1  - Ru, Arnoud H. de
A1  - Claas, Frans H. J.
A1  - Mulder, Arend
A1  - Tampé, Robert
A1  - Veelen, Peter A. van
A1  - Halenius, Anne
A1  - Spaapen, Robbert M.
T1  - PAKC: A novel panel of HLA class I antigen presentation machinery knockout cells from the same genetic origin
T2  - European Journal of Immunology
N2  - A single model system for integrative studies on multiple facets of antigen presentation is lacking. PAKC is a novel panel of ten cell lines knocked out for individual components of the HLA class I antigen presentation pathway. PAKC will accelerate HLA-I research in the fields of oncology, infectiology, and autoimmunity.
KW  - APM
KW  - antigen presentation
KW  - HLA class I
KW  - CRISPR/Cas9
KW  - MHC
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/73286
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-732869
VL  - 51
IS  - 3
SP  - 734
EP  - 737
PB  - Wiley-VCH
CY  - Weinheim
ER  -