TY - INPR A1 - Lehrach, Hans A1 - Curtis, Jon A1 - Lange, Bodo A1 - Ogilvie, Lesley A. A1 - Gauss, Richard A1 - Steininger, Christoph A1 - Scholz, Erhard A1 - Kreck, Matthias T1 - Proposal of a population wide genome-based testing for Covid-19 T2 - Scientific Reports N2 - Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel tool for controlling the COVID-19 pandemic. The key element is a method for a population-scale PCR-based testing, applied on a systematic and repeated basis. For this we have developed a low cost, highly sensitive virus-genome-based test. Using Germany as an example, we demonstrate by using a mathematical model, how useful this strategy could have been in controlling the pandemic. We show using real-world examples how this might be implemented on a mass scale and discuss the feasibility of this approach. Y1 - 2022 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/73620 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-736206 SN - 2045-2322 VL - 12 IS - 5618 PB - Macmillan Publishers Limited, part of Springer Nature CY - London ER -