TY  - JOUR
A1  - Stauch, Benjamin J.
A1  - Peter, Alina
A1  - Schuler, Heike
A1  - Fries, Pascal
T1  - Stimulus-specific plasticity in human visual gamma-band activity and functional connectivity
T2  - eLife
N2  - Under natural conditions, the visual system often sees a given input repeatedly. This provides an opportunity to optimize processing of the repeated stimuli. Stimulus repetition has been shown to strongly modulate neuronal-gamma band synchronization, yet crucial questions remained open. Here we used magnetoencephalography in 30 human subjects and find that gamma decreases across ≈10 repetitions and then increases across further repetitions, revealing plastic changes of the activated neuronal circuits. Crucially, increases induced by one stimulus did not affect responses to other stimuli, demonstrating stimulus specificity. Changes partially persisted when the inducing stimulus was repeated after 25 minutes of intervening stimuli. They were strongest in early visual cortex and increased interareal feedforward influences. Our results suggest that early visual cortex gamma synchronization enables adaptive neuronal processing of recurring stimuli. These and previously reported changes might be due to an interaction of oscillatory dynamics with established synaptic plasticity mechanisms.
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62741
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-627410
SN  - 2050-084X
N1  - PF acknowledges grant support by DFG (SPP 1665 FR2557/1-1, FOR 1847 FR2557/2-1, FR2557/5-1-CORNET, FR2557/6-1-NeuroTMR, FR2557/7-1 DualStreams), EU (FP7-604102-HBP, FP7-600730-Magnetrodes), a European Young Investigator Award, NIH (1U54MH091657-WU-Minn-Consortium-HCP), and LOEWE (NeFF).
VL  - 10
IS  - art. e68240
SP  - 1
EP  - 22
PB  - eLife Sciences Publications
CY  - Cambridge
ER  -