TY  - JOUR
A1  - Büttner, Stefan
A1  - Bachmann, Jürgen
A1  - Geiger, Helmut
A1  - Obermüller, Nicholas
T1  - Long-term vaptan treatment of idiopathic SIADH in an octogenarian
T2  - Journal of Clinical Medicine
N2  - Hyponatremia is the most common and by far underestimated electrolyte disorder in clinical practice. Especially in elderly patients, treatment of symptomatic hyponatremia is challenging. Herein we describe the case of an octogenarian with recurrent symptomatic hyponatremia due to idiopathic syndrome of inappropriate antidiuretic hormone release (SIADH). Fluid restriction was insufficient to prevent repeated episodes of hyponatremia complicated by falls and coma. After introduction of a low-dose therapy with tolvaptan, serum sodium levels as well as the clinical condition were stable under vaptan therapy, without any relapse for more than six years now. This case demonstrates that long-term tolvaptan treatment for hyponatremia caused by SIADH is safe and well tolerated, even in the elderly.
KW  - hyponatremia
KW  - SIADH
KW  - tolvaptan
KW  - elderly
Y1  - 2017
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/42634
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-426345
SN  - 2077-0383
N1  - © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
VL  - 6
IS  - 3, Art. 28
SP  - 1
EP  - 6
PB  - MDPI
CY  - Basel
ER  -