TY  - JOUR
A1  - Lee, Taik Jong
A1  - Cho, Jeong Mok
A1  - Jo, Taehee
A1  - Han, Woo Yeon
A1  - Maldonado, Andrés A.
A1  - Eom, Jin Sup
A1  - Kim, Eun Key
T1  - Volumetric changes of the pedicled transverse rectus abdominis musculocutaneous flap and the contralateral native breast during long-term follow-up
T2  - Archives of aesthetic plastic surgery
N2  - Background: Serial volumetric changes of reconstructed breasts have not been studied in detail. In this study, we analyzed serial volumetric changes of reconstructed and contralateral normal breasts during long-term follow-up, with a focus on the effect of various adjuvant therapies.
Methods: Among all patients who underwent immediate breast reconstruction with a unilateral pedicled transverse rectus abdominis musculocutaneous (p-TRAM) flap, 42 patients with valid data from ≥3 postoperative positron emission tomography-computed tomography (PET-CT) scans were included. The volumes of the reconstructed and normal breasts were measured, and the ratio of flap volume to that of the contralateral breast was calculated. Serial changes in volume and the volume ratio were described, and the effects of chemotherapy, radiation therapy, and hormone therapy on volumetric changes were analyzed.
Results: The mean interval between the initial reconstruction and each PET-CT scan was 16.5, 30, and 51 months respectively. Thirty-five, 36, and 10 patients received chemotherapy, hormone therapy, and radiation therapy, respectively. The flap volume at each measurement was 531.0, 539.6, and 538.0 cm3, and the contralateral breast volume was 472.8, 486.4, and 500.8 cm3, respectively. The volume ratio decreased from 115.1% to 113.4%, and finally to 109.6% (P=0.02). Adjuvant therapies showed no significant effects.
Conclusions: We demonstrated that the p-TRAM flap maintained its volume over a long-term follow up, while the volume of the contralateral native breast slowly increased. Moreover, adjuvant breast cancer therapies had no statistically significant effects on the volume of the reconstructed p-TRAM flaps or the contralateral native breasts.
KW  - Breast neoplasms
KW  - Drug therapy
KW  - Mammaplasty
KW  - Radiotherapy
KW  - Surgery
KW  - plastic
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/54682
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-546829
SN  - 2288-9337
SN  - 2234-0831
N1  - Copyright © 2019 The Korean Society for Aesthetic Plastic Surgery. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. www.e-aaps.org
VL  - 25
IS  - 3
SP  - 95
EP  - 102
PB  - Korean Society for Aesthetic Plastic Surgery ; Academya Publishing Co.
CY  - Seoul ; Anyang
ER  -