TY  - JOUR
A1  - Höh, Robert Benedikt
A1  - Wenzel, Mike
A1  - Müller, Matthias
A1  - Wittler, Clarissa
A1  - Schlenke, Eva
A1  - Hohenhorst, Jan L.
A1  - Köllermann, Jens
A1  - Steuber, Thomas
A1  - Graefen, Markus
A1  - Tilki, Derya
A1  - Bernatz, Simon
A1  - Karakiewicz, Pierre I.
A1  - Preißer, Felix
A1  - Becker, Andreas
A1  - Kluth, Luis
A1  - Mandel, Philipp
A1  - Chun, Felix
T1  - Urethral sphincter length but not prostatic apex shape in preoperative MRI is associated with mid-term continence rates after radical prostatectomy
T2  - Diagnostics
N2  - Background: To test the impact of urethral sphincter length (USL) and anatomic variants of prostatic apex (Lee-type classification) in preoperative multiparametric magnet resonance imaging (mpMRI) on mid-term continence in prostate cancer patients treated with radical prostatectomy (RP). Methods: We relied on an institutional tertiary-care database to identify patients who underwent RP between 03/2018 and 12/2019 with preoperative mpMRI and data available on mid-term (>6 months post-surgery) urinary continence, defined as usage 0/1 (-safety) pad/24 h. Univariable and multivariable logistic regression models were fitted to test for predictor status of USL and prostatic apex variants, defined in mpMRI measurements. Results: Of 68 eligible patients, rate of mid-term urinary continence was 81% (n = 55). Median coronal (15.1 vs. 12.5 mm) and sagittal (15.4 vs. 11.1 mm) USL were longer in patients reporting urinary continence in mid-term follow-up (both p < 0.01). No difference was recorded for prostatic apex variants distribution (Lee-type) between continent vs. incontinent patients (p = 0.4). In separate multivariable logistic regression models, coronal (odds ratio (OR): 1.35) and sagittal (OR: 1.67) USL, but not Lee-type, were independent predictors for mid-term continence. Conclusion: USL, but not apex anatomy, in preoperative mpMRI was associated with higher rates of urinary continence at mid-term follow-up.
KW  - Lee-type
KW  - apex
KW  - functional outcome
KW  - membranous urethra
KW  - mid-term urinary continence
KW  - prostate cancer
KW  - radical prostatectomy
Y1  - 2022
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/83173
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-831737
SN  - 2075-4418
VL  - 12
IS  - 3, art. 701
SP  - 1
EP  - 13
PB  - MDPI
CY  - Basel
ER  -