TY  - JOUR
A1  - Barnbrock, Anke
A1  - Salzmann-Manrique, Emilia
A1  - Sänger, Nicole
A1  - Fiegel, Henning C.
A1  - Ochsendorf, Falk
A1  - Klingebiel, Thomas
A1  - Bader, Peter
A1  - Jarisch, Andrea
T1  - How can fertility counseling be implemented for every newly diagnosed pediatric patient facing gonadotoxic treatment? : A single-center experience
T2  - Annals of hematology
N2  - Since the survival rates of pediatric patients undergoing cancer treatment or hematopoietic stem cell transplantation (HSCT) have increased rapidly in recent decades, the late effects of treatment are now an important focus of patient care. Access to fertility preservation (FP) procedures as well as their financing differs considerably across Europe. However, some countries in Europe have recently changed the legal basis for financing FP procedures; therefore, the implementation of structures is mandatory to give patients access to FP. In this prospective cohort study, we characterized the process for establishing pediatric fertility counseling, including the development of an in-house standard procedure for recommendations regarding FP with potentially gonadotoxic treatment and valuating data from all FP counseling sessions. All data concerning patient characteristics (pubertal status, disease group) and recommendation of FP measures were prospectively collected and adoption of FP measures analyzed. Prior to the establishment of a structured process for FP in our pediatric oncology and stem cell transplantation center, there was no standardized FP counseling. We demonstrate that with the establishment of an inhouse standard procedure, it is possible to give consistent yet individualized FP counseling to approximately 90% of our patients facing gonadotoxic treatment, counseling over 200 patients between 2017 and 2019. This pilot study could potentially be adapted in other pediatric hematology, oncology, and stem cell transplantation centers to allow a more standardized handling of FP counseling for all patients facing gonadotoxic treatment.
KW  - Fertility counseling
KW  - Pediatric oncology
KW  - Pediatric stem cell transplantation
KW  - Indication for fertility preservation
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/64032
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-640320
SN  - 1432-0584
N1  - Open Access funding enabled and organized by Projekt DEAL. Funding was available through a parents' association, including for a physician scientist position (50%), as the German health insurance system did not yet cover the costs as mentioned in the manuscript. Otherwise, funding was used to support the families covering the costs of the fertility-preserving procedures.
N1  - We thank the parents' association 'Hilfe für Krebskranke Kinder Frankfurt e.V.' for funding the project.
VL  - 100
SP  - 2831
EP  - 2841
PB  - Springer
CY  - Berlin ; Heidelberg ; New York
ER  -