TY  - JOUR
A1  - Yoshida, Ken
A1  - Kotsuma, Tadayuki
A1  - Akiyama, Hironori
A1  - Yamazaki, Hideya
A1  - Takenaka, Tadashi
A1  - Masui, Koji
A1  - Tsujimoto, Yutaka
A1  - Murakami, Naoya
A1  - Uesugi, Yasuo
A1  - Shimbo, Taiju
A1  - Yoshikawa, Nobuhiko
A1  - Yoshioka, Hiroto
A1  - Nakata, Mio
A1  - Arika, Takumi
A1  - Takaoka, Yuji
A1  - Tanaka, Eiichi
A1  - Tselis, Nikolaos
T1  - A new implant device to prevent edema-associated underdosage in high-dose-rate interstitial brachytherapy of mobile tongue cancer
T2  - Journal of contemporary brachytherapy
N2  - Purpose: Tongue edema is a potential cause of treatment target underdosage in high-dose-rate interstitial brachytherapy (HDR-ISBT) of mobile tongue cancer. To prevent such edema-associated alteration of dosimetry, we developed a special silicon device. In this report we communicate our initial experience with two mobile tongue cancer patients whom we treated using this new device.
Material and methods: The device consists of silicone tubes with a fixed width and scalable length depending on tongue size. These tubes are lined and fixed like a palisade, allowing the device to be used also as a template. The device is placed next to the lateral border of the tongue and on the floor of the mouth. In addition, a vinyl template can be placed on the dorsal tongue surface with both devices combined for implantation guidance. Between June and August 2012, two patients with locally confined tongue cancer were treated.
Results: Between June and August 2012, two mobile tongue cancer patients classified as cT2N0M0 were treated with HDR-ISBT using the silicone device. They underwent ISBT as monotherapy with fractional doses of 6.0 Gy up to a total physical dose of 54.0 Gy. The D90 (CTV) values of both patients were 6.3 Gy and 6.6 Gy and the D2cc (mandible) values were 3.4 Gy and 2.6 Gy, respectively. At present, both patients remain without local disease recurrence at 60 and 56 months after ISBT, respectively.
Conclusions: The described silicone device has the potential to prevent underdosage to the treatment target related to tongue edema. It has been shown to be safe and easy to implement.
KW  - tongue edema
KW  - silicone device
KW  - high-dose-rate interstitial brachytherapy
KW  - mobile tongue cancer
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53064
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-530646
SN  - 2081-2841
SN  - 1689-832X
N1  - Copyright: © 2019 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
VL  - 11
IS  - 6
SP  - 573
EP  - 578
PB  - Termedia
CY  - Poznań
ER  -