TY  - THES
A1  - Hanspach, Gerd Werner Günter
T1  - Structure, assembly and dynamics of H/ACA-Ribonucleoproteins
N2  - H/ACA-RNPs are involved in RNA guided pseudouridylation of rRNAs and snRNAs. In this thesis I reconstituted active and labeled archaeal as well as eukaryotic H/ACA-RNPs and studied the structural dynamics of complex assembly and pseudouridine formation. Single molecule FRET spectroscopy was used as method of analysis to study structure, assembly and dynamics of these important complexes.
KW  - smFRET
KW  - H/ACA-RNP
KW  - Pseudouridine
KW  - Pseudouridylation
KW  - Ribonucleoproteins
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/57446
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-574468
CY  - Frankfurt am Main
ER  -