TY - JOUR A1 - Freisleben, Hans-Joachim T1 - The Main (Glyco) Phospholipid (MPL) of Thermoplasma acidophilum T2 - International journal of molecular sciences N2 - The main phospholipid (MPL) of Thermoplasma acidophilum DSM 1728 was isolated, purified and physico-chemically characterized by differential scanning calorimetry (DSC)/differential thermal analysis (DTA) for its thermotropic behavior, alone and in mixtures with other lipids, cholesterol, hydrophobic peptides and pore-forming ionophores. Model membranes from MPL were investigated; black lipid membrane, Langmuir-Blodgett monolayer, and liposomes. Laboratory results were compared to computer simulation. MPL forms stable and resistant liposomes with highly proton-impermeable membrane and mixes at certain degree with common bilayer-forming lipids. Monomeric bacteriorhodopsin and ATP synthase from Micrococcus luteus were co-reconstituted and light-driven ATP synthesis measured. This review reports about almost four decades of research on Thermoplasma membrane and its MPL as well as transfer of this research to Thermoplasma species recently isolated from Indonesian volcanoes. KW - Thermoplasma acidophilum KW - Thermoplasma volcanium KW - tetraether lipid KW - main phospholipid KW - black lipid membrane KW - Langmuir-Blodgett monolayer KW - liposomes KW - proton permeability KW - bacteriorhodopsin reconstitution KW - light-driven ATP synthesis Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/54446 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-544460 N1 - This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 20 IS - 5217 PB - MDPI CY - Basel ER -