TY - JOUR A1 - Nickles, Katrin A1 - Krebs, Mischa A1 - Schacher, Beate A1 - Petsos, Hari A1 - Eickholz, Peter T1 - Long-term results after placing dental implants in patients with Papillon-Lefèvre syndrome: results 2.5–20 years after implant insertion T2 - Journal of Clinical Medicine N2 - Aim: A retrospective evaluation of patients with Papillon-Lefèvre syndrome (PLS) treated with dental implants to identify factors that may influence treatment outcomes. Methods: All PLS patients with dental implants currently registered at the Department of Periodontology, Goethe-University Frankfurt (20–38 years; mean: 29.6 years), were recruited. Five patients from three families (two pairs of siblings) with a total of 48 dental implants (inserted in different dental institutions) were included with a follow-up time of 2.5–20 years (mean: 10.4 years). Results: Implant failure occurred in three patients (at least 15 implants). Nearly all patients demonstrated peri-implantitis in more or less advanced stages; 60% of patients demonstrated bone loss ≥50% around the implants. Two patients did not follow any supportive therapy. Conclusions: Implants in PLS patients who did not follow any maintenance programme had a high risk of peri-implantitis and implant loss. KW - dental implants KW - Papillon-Lefèvre syndrome KW - peri-implantitis KW - periodontitis KW - long-term results Y1 - 2022 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/69271 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-692718 SN - 2077-0383 N1 - The microbiological examinations in four patients were partially funded by Carpegen GmbH, Münster. N1 - This study was kindly supported by Carpegen GmbH, Münster, Germany. VL - 11 IS - 9, art. 2438 SP - 1 EP - 10 PB - MDPI CY - Basel ER -