TY - JOUR A1 - Bohmann, Ferdinand A1 - Gruber, Katharina A1 - Kurka, Natalia A1 - Willems, Laurent Maximilian A1 - Herrmann, Eva A1 - Du Mesnil de Rochemont, Richard Klaus Frieder A1 - Scholz, Peter A1 - Rai, Heike A1 - Zickler, Philipp Patrick A1 - Ertl, Michael A1 - Berlis, Ansgar A1 - Poli, Sven A1 - Mengel, Annerose A1 - Ringleb, Peter A. A1 - Nagel, Simon A1 - Pfaff, Johannes A1 - Wollenweber, Frank Arne A1 - Kellert, Lars A1 - Herzberg, Moriz A1 - Köhler, Luzie Katharina A1 - Häusler, Karl Georg A1 - Alegiani, Anna A1 - Schubert, Charlotte A1 - Brekenfeld, Caspar A1 - Doppler, Christopher Emanuel Julian A1 - Onur, Özgür Abdullah A1 - Kabbasch, Christoph A1 - Manser, Tanja A1 - Steinmetz, Helmuth A1 - Pfeilschifter, Waltraud T1 - Simulation-based training improves process times in acute stroke care (STREAM) T2 - European journal of neurology N2 - Background: The objective of the STREAM Trial was to evaluate the effect of simulation training on process times in acute stroke care. Methods: The multicenter prospective interventional STREAM Trial was conducted between 10/2017 and 04/2019 at seven tertiary care neurocenters in Germany with a pre- and post-interventional observation phase. We recorded patient characteristics, acute stroke care process times, stroke team composition and simulation experience for consecutive direct-to-center patients receiving intravenous thrombolysis (IVT) and/or endovascular therapy (EVT). The intervention consisted of a composite intervention centered around stroke-specific in situ simulation training. Primary outcome measure was the ‘door-to-needle’ time (DTN) for IVT. Secondary outcome measures included process times of EVT and measures taken to streamline the pre-existing treatment algorithm. Results: The effect of the STREAM intervention on the process times of all acute stroke operations was neutral. However, secondary analyses showed a DTN reduction of 5 min from 38 min pre-intervention (interquartile range [IQR] 25–43 min) to 33 min (IQR 23–39 min, p = 0.03) post-intervention achieved by simulation-experienced stroke teams. Concerning EVT, we found significantly shorter door-to-groin times in patients who were treated by teams with simulation experience as compared to simulation-naive teams in the post-interventional phase (−21 min, simulation-naive: 95 min, IQR 69–111 vs. simulation-experienced: 74 min, IQR 51–92, p = 0.04). Conclusion: An intervention combining workflow refinement and simulation-based stroke team training has the potential to improve process times in acute stroke care. KW - CRM KW - simulation KW - stroke KW - thrombolysis KW - training Y1 - 2021 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/74630 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-746304 SN - 1468-1331 N1 - The study was funded by Stryker Neurovascular (grant to W.P.). The funding source was not involved in study design, monitoring, data collection, statistical analyses, interpretation of results, or manuscript writing, Open Access funding enabled and organized by Projekt DEAL. WOA Institution: Goethe-Universitat Frankfurt am Main Blended DEAL: Projekt DEAL. VL - 29 IS - 1 SP - 138 EP - 148 PB - Wiley-Blackwell CY - Oxford [u.a.] ER -