TY  - JOUR
A1  - Zangl, Rene
A1  - Morgner, Nina
T1  - Wie kleine Amyloid-β-Peptide zum großen Problem im Gehirn werden können
T2  - Biospektrum
N2  - The formation of amyloid-β oligomers plays a key role in the onset of Alzheimer’s disease. We investigated the aggregation of amyloid-β oligomers by mass spectrometry and ion mobility spectrometry, revealing those structural properties, which lead to the formation of mature fibrils. We can show that the arrangement of the first oligomers is crucial for the topology of the resulting species, leading to the formation of non-toxic aggregates or fibrils.
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/69547
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-695474
SN  - 1868-6249
N1  - Open Access funding enabled and organized by Projekt DEAL.
VL  - 27
IS  - 7
SP  - 705
EP  - 708
PB  - Spektrum
CY  - Heidelberg
ER  -