TY  - JOUR
A1  - Petsos, Hari
A1  - Koronna, Ilona
A1  - Ramich, Tatjana
A1  - Nickles, Katrin
A1  - Dannewitz, Bettina
A1  - Schacher, Beate
A1  - Eickholz, Peter
T1  - Ten-year stability of clinical attachment after regenerative treatment of infrabony defects and controls
T2  - Journal of Clinical Medicine
N2  - Background: A similar long-term stable clinical attachment level (CAL) of infrabony defects (IBDs) after regenerative treatment compared to control teeth would indicate a high level of stability resulting from the regenerative approach. Methods: Patients with a regeneratively treated IBD were screened 120 ± 12 months postoperatively for eligibility for study participation, and were included if complete baseline and 12-month examinations (plaque (PlI), periodontal probing depth (PPD), CAL) were available and a respective control tooth could be identified. Re-examination included clinical examination (PPD, CAL, PlI/GI, bleeding on probing, plaque control record, gingival bleeding index). Results: A total of 27 patients (16 females; age (median; lower/upper quartile): 57.0; 44.0/60.0 years; 6 smokers) contributed 27 IBDs (test), for each of which a control tooth was identified. Five test teeth (18.5%) were lost between 12 and 120 months. The remaining 22 test teeth revealed a significant CAL gain after 1 (2.5 mm; 1.0/4.0 mm, p < 0.0001) and 10 (2.5 mm; 0.5/3.5 mm, p < 0.0001) years, whereas control teeth were stable (1 year: 0.0 mm; 0.0/1.0 mm, p = 0.396; 10 years: 0.0 mm; −1.0/1.5 mm, p = 0.215). The study did not detect any significant CAL change between 1 and 10 years for test (−0.5 mm; −1.0/0.5 mm, p = 0.414) and control teeth (0.0 mm; −1.0/1.0 mm, p = 0.739). In 15 patients, test and control teeth revealed stable CAL values between 12 and 120 months. Conclusion: Regenerative treatment of IBDs exhibited stability comparable to non-surgically treated, periodontally reduced sites over a 10-year period.
KW  - attachment loss
KW  - enamel matrix derivatives
KW  - guided tissue regeneration
KW  - periodontitis
KW  - surgical procedures
KW  - tooth loss
Y1  - 2022
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/80035
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-800358
SN  - 2077-0383
N1  - This research was partially self-funded by the authors and their institutions, as well as by a research grant provided by the Moessner Stiftung (Frankfurt/Main, Germany) to the Department of Periodontology of the Center for Dentistry and Oral Medicine of Goethe University Frankfurt am Main, Germany.
VL  - 11
IS  - 3, art. 543
SP  - 1
EP  - 13
PB  - MDPI
CY  - Basel
ER  -