TY  - JOUR
A1  - Mosiello, Giovanni
A1  - Safder, Shaista
A1  - Marshall, David
A1  - Rolle, Udo
A1  - Benninga, Marc A.
T1  - Neurogenic bowel dysfunction in children and adolescents
T2  - Journal of Clinical Medicine
N2  - Neurogenic/neuropathic bowel dysfunction (NBD) is common in children who are affected by congenital and acquired neurological disease, and negatively impacts quality of life. In the past, NBD received less attention than neurogenic bladder, generally being considered only in spina bifida (the most common cause of pediatric NBD). Many methods of conservative and medical management of NBD are reported, including relatively recently Transanal Irrigation (TAI). Based on the literature and personal experience, an expert group (pediatric urologists/surgeons/gastroenterologists with specific experience in NBD) focused on NBD in children and adolescents. A statement document was created using a modified Delphi method. The range of causes of pediatric NBD are discussed in this paper. The various therapeutic approaches are presented to improve clinical management. The population of children and adolescents with NBD is increasing, due both to the higher survival rate and better diagnosis. While NBD is relatively predictable in producing either constipation or fecal incontinence, or both, its various effects on each patient will depend on a wide range of underlying causes and accompanying comorbidities. For this reason, management of NBD should be tailored individually with a combined multidisciplinary therapy appropriate for the status of the affected child and caregivers.
KW  - neurogenic bowel
KW  - bowel dysfunction
KW  - constipation
KW  - fecal incontinence
KW  - pediatric
KW  - children
KW  - adolescent
KW  - spina bifida
KW  - anorectal malformation
KW  - cerebral palsy
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62133
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-621331
SN  - 2077-0383
VL  - 10
IS  - 8, art. 1669
SP  - 1
EP  - 30
PB  - MDPI
CY  - Basel
ER  -