TY  - JOUR
A1  - Friebe, Andreas
A1  - Sandner, Peter
A1  - Schmidtko, Achim
T1  - Meeting report of the 8th International Conference on cGMP "cGMP: generators, effectors, and therapeutic implications" at Bamberg, Germany, from June 23 to 25, 2017
T2  - Naunyn-Schmiedeberg's archives of pharmacology
N2  - Although the Nobel Prize for the discovery of nitric oxide (NO) dates back almost 20 years now, the knowledge about cGMP signaling is still constantly increasing. It looks even so that our understanding of the role of the soluble guanylyl cyclase (sGC) and particulate guanylyl cyclase (pGC) in health and disease is in many aspects at the beginning and far from being understood. This holds even true for the therapeutic impact of innovative drugs acting on both the NO/sGC and the pGC pathways. Since cGMP, as second messenger, is involved in the pathogenesis of numerous diseases within the cardiovascular, pulmonary, renal, and endocrine systems and also plays a role in neuronal, sensory, and tumor processes, drug applications might be quite broad. On the 8th International Conference on cGMP, held in Bamberg, Germany, world leading experts came together to discuss these topics. All aspects of cGMP research from the basic understanding of cGMP signaling to clinical applicability were discussed in depth. In addition, present and future therapeutic applications of cGMP-modulating pharmacotherapy were presented (http://www.cyclicgmp.net/index.html).
KW  - cGMP
KW  - Guanylyl cyclases
KW  - Phosphodiesterases
KW  - Nitric oxide
KW  - Natriuretic peptides
Y1  - 2017
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46584
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-465845
SN  - 1432-1912
SN  - 0028-1298
N1  - © Springer-Verlag GmbH Germany 2017
N1  - Correction erschienen in: Naunyn-Schmiedeberg's Archives of Pharmacology, 391.2018, Nr. 3, S. 347–347, doi:10.1007/s00210-018-1472-x, darin Lizenz korrigiert zu CC BY 4.0
VL  - 390
IS  - 12
SP  - 1177
EP  - 1188
PB  - Springer
CY  - Berlin ; Heidelberg
ER  -