TY  - JOUR
A1  - Behrends, Christian
A1  - Fulda, Simone
T1  - Receptor proteins in selective autophagy
T2  - International journal of cell biology
N2  - Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates. Bifunctional autophagy receptors play a key role in selective autophagy by tethering cargo to the site of autophagosomal engulfment. While the identity of molecular components involved in selective autophagy has been revealed at least to some extent, we are only beginning to understand how selectivity is achieved in this process. Here, we summarize the mechanistic and structural basis of receptor-mediated selective autophagy.
Y1  - 2012
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/24351
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-243514
SN  - 1687-8884
SN  - 1687-8876
VL  - 2012
IS  - Article ID 673290
PB  - New York, NY
CY  - Hindawi
ER  -