TY - JOUR A1 - Fulda, Simone T1 - Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link T2 - Oncotarget N2 - The proteasome inhibitor Bortezomib has been identified as a potent enhancer of TRAIL-induced apoptosis in several human cancers. However, the identification of the underlying molecular mechanisms of this synergistic cell death induction has been ongoing over the last years. A recent study identifies a new mechanism of action for the synergism of TRAIL and Bortezomib. KW - cancer KW - apoptosis KW - chemotherapy KW - proteasome inhibitor KW - TRAIL Y1 - 2011 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/22359 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30-102383 UR - http://www.impactjournals.com/oncotarget/index.php?journal=oncotarget&page=article&op=view&path[]=277&path[]=421 SN - 1949-2553 N1 - Copyright: © Fulda. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. VL - 2 IS - 5 SP - 418 EP - 421 PB - Impact Journals LLC CY - [S.l.] ER -