TY - JOUR A1 - Harapan, Harapan A1 - Anwar, Samsul A1 - Bustaman, Aslam A1 - Radiansyah, Arsil A1 - Angraini, Pradiba A1 - Fasli, Riny A1 - Salwiyadi, Salwiyadi A1 - Bastian, Reza Akbar A1 - Oktiviyari, Ade A1 - Akmal, Imaduddin A1 - Iqbalamin, Muhammad A1 - Adil, Jamalul A1 - Henrizal, Fenni A1 - Darmayanti, Darmayanti A1 - Pratama, Rovy A1 - Fajar, Jonny Karunia A1 - Setiawan, Abdul Malik A1 - Imrie, Allison A1 - Kuch, Ulrich A1 - Groneberg, Jan David Alexander A1 - Sasmono, R. Tedjo A1 - Dhimal, Meghnath A1 - Müller, Ruth T1 - Community willingness to participate in a dengue study in Aceh province, Indonesia T2 - PLoS One N2 - Background: Dengue virus infection is the most rapidly spreading vector-borne disease in the world. Essential research on dengue virus transmission and its prevention requires community participation. Therefore, it is crucial to understand the factors that are associated with the willingness of communities in high prevalence areas to participate in dengue research. The aim of this study was to explore factors associated with the willingness of healthy community members in Aceh province, Indonesia, to participate in dengue research that would require phlebotomy. Methodology/Principal Findings: A community-based cross-sectional study was carried out in nine regencies and municipalities of Aceh from November 2014 to March 2015. Interviews using a set of validated questionnaires were conducted to collect data on demography, history of dengue infection, socioeconomic status, and knowledge, attitude and practice regarding dengue fever. Two-step logistic regression and Spearman’s rank correlation (rs) analysis were used to assess the influence of independent variables on dependent variables. Among 535 participants, less than 20% had a good willingness to participate in the dengue study. The factors associated with good willingness to participate were being female, working as a civil servant, private employee or entrepreneur, having a high socioeconomic status and good knowledge, attitude and practice regarding dengue. Good knowledge and attitude regarding dengue were positive independent predictors of willingness to participate (OR: 2.30 [95% CI: 1.36–3.90] and 3.73 [95% CI: 2.24–6.21], respectively). Conclusion/Significance: The willingness to participate in dengue research is very low among community members in Aceh, and the two most important associated factors are knowledge and attitude regarding dengue. To increase participation rate, efforts to improve the knowledge and attitude of community members regarding dengue fever and dengue-related research is required before such studies are launched. Y1 - 2016 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/41452 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-414527 SN - 1932-6203 N1 - Copyright: © 2016 Harapan et al. This is an open access article distributed under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. VL - 11 IS - (7): e0159139 SP - 1 EP - 15 PB - PLoS CY - Lawrence, Kan. ER -