TY  - JOUR
A1  - Rhiem, Kerstin E. M.
A1  - Auber, Bernd
A1  - Briest, Susanne
A1  - Dikow, Nicola
A1  - Ditsch, Nina
A1  - Dragicevic, Neda
A1  - Grill, Sabine
A1  - Hahnen, Eric Thomas
A1  - Horváth, Judit
A1  - Jäger, Bernadette
A1  - Kast, Karin
A1  - Kiechle, Marion
A1  - Leinert, Elena
A1  - Morlot, Susanne
A1  - Püsken, Michael
A1  - Schäfer, Dieter
A1  - Schott, Sarah
A1  - Schroeder, Christopher Maximilian
A1  - Siebers-Renelt, Ulrike
A1  - Solbach, Christine
A1  - Weber-Lassalle, Nana-Maureen
A1  - Witzel, Isabell
A1  - Zeder-Göß, Christine
A1  - Schmutzler, Rita
T1  - Consensus Recommendations of the German Consortium for Hereditary Breast and Ovarian Cancer
T2  - Breast care
N2  - Background: The German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC) has established a multigene panel (TruRisk®) for the analysis of risk genes for familial breast and ovarian cancer. Summary: An interdisciplinary team of experts from the GC-HBOC has evaluated the available data on risk modification in the presence of pathogenic mutations in these genes based on a structured literature search and through a formal consensus process. Key Messages: The goal of this work is to better assess individual disease risk and, on this basis, to derive clinical recommendations for patient counseling and care at the centers of the GC-HBOC from the initial consultation prior to genetic testing to the use of individual risk-adapted preventive/therapeutic measures.
KW  - Consensus
KW  - Panel testing
KW  - Hereditary breast cancer
KW  - Hereditary ovarian cancer
KW  - BRCA1
KW  - BRCA2
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/62930
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-629304
SN  - 1661-3805
VL  - 17
IS  - 2
SP  - 199
EP  - 207
PB  - Karger
CY  - Basel
ER  -