TY - JOUR A1 - Balat, Ahmed el- A1 - Wilde, Rudy Leon de A1 - Schmeil, Iryna A1 - Tahmasbi Rad, Morva A1 - Bogdanyova, Sandra A1 - Fathi, Ali A1 - Becker, Sven T1 - Modern myoma treatment in the last 20 years : a review of the literature T2 - BioMed research international N2 - Myomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans with the highly specific process of childbirth from an upright position and the resulting need for greatly increased “expulsive” forces during labor. Myomas might be the price our species pays for our bipedal and highly intelligent existence. Myomas affect, with some variability, all ethnic groups and approximately 50% of all women during their lifetime. While some remain asymptomatic, myomas can cause significant and sometimes life-threatening uterine bleeding, pain, infertility, and, in extreme cases, ureteral obstruction and death. Traditionally, over 50% of all hysterectomies were performed for fibroids, leading to a significant healthcare burden. In this article, we review the developments of the past 20 years with regard to multiple new treatment strategies that have evolved during this time. Y1 - 2018 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46383 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-463831 SN - 2314-6141 SN - 2314-6133 N1 - Copyright © 2018 Ahmed El-Balat et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 2018 IS - Art. 4593875 SP - 1 EP - 6 PB - Hindawi CY - New York [u. a.] ER -