TY - INPR A1 - Wehrenberg, Gerrit A1 - Tokarska, Małgorzata A1 - Cocchiararo, Berardino A1 - Nowak, Carsten T1 - A reduced SNP panel optimised for non-invasive genetic assessment of a genetically impoverished conservation icon, the European bison T2 - bioRxiv N2 - The European bison was saved from the brink of extinction due to considerable conservation efforts since the early 20th century. The current global population of > 9,500 individuals is the result of successful ex situ breeding based on a stock of only 12 founders, resulting in an extremely low level of genetic variability. Due to the low allelic diversity, traditional molecular tools, such as microsatellites, fail to provide sufficient resolution for accurate genetic assessments in European bison, let alone from non-invasive samples. Here, we present a SNP panel for accurate high-resolution genotyping of European bison, which is suitable for a wide variety of sample types. The panel accommodates 96 markers allowing for individual and parental assignment, sex determination, breeding line discrimination, and cross-species detection. Two applications were shown to be utilisable in further Bos species with potential conservation significance. The new SNP panel will allow to tackle crucial tasks in European bison conservation, including the genetic monitoring of reintroduced populations, and a molecular assessment of pedigree data documented in the world’s first studbook of a threatened species. Y1 - 2023 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/73543 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-735437 IS - 2023.04.01.535110 ER -