TY - JOUR A1 - Wilke, Jan A1 - Schleip, Robert A1 - Klingler, Werner A1 - Stecco, Carla T1 - The lumbodorsal fascia as a potential source of low back pain : a narrative review T2 - BioMed research international N2 - The lumbodorsal fascia (LF) has been proposed to represent a possible source of idiopathic low back pain. In fact, histological studies have demonstrated the presence of nociceptive free nerve endings within the LF, which, furthermore, appear to exhibit morphological changes in patients with chronic low back pain. However, it is unclear how these characteristics relate to the aetiology of the pain. In vivo elicitation of back pain via experimental stimulation of the LF suggests that dorsal horn neurons react by increasing their excitability. Such sensitization of fascia-related dorsal horn neurons, in turn, could be related to microinjuries and/or inflammation in the LF. Despite available data point towards a significant role of the LF in low back pain, further studies are needed to better understand the involved neurophysiological dynamics. Y1 - 2017 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/43675 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-436755 SN - 2314-6141 SN - 2314-6133 N1 - Copyright © 2017 Jan Wilke et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 2017 IS - Art. 5349620 SP - 1 EP - 6 PB - Hindawi CY - New York [u. a.] ER -