TY  - THES
A1  - Heinrich, Eva-Marie
T1  - Posttranscriptional regulation of the microRNA-17-92a cluster
N2  - By far not all genetic information is expressed by mRNA coding regions of the DNA. 98% of the human genome is not encoding for proteins. Therefore, these non-coding regions have been considered as “junk DNA” for a long time [1, 2]. The last years, new high throughput sequencing techniques have allowed the elucidation of the heterogeneous population of non-coding RNAs (ncRNAs, Table 1). RNAs longer than 200 nucleotides (nt) belong to the family of long non-coding RNAs (lncRNAs). They can exhibit numerous functions: The biggest family of RNAs is represented by the ribosomal RNAs (rRNAs). Together with the transfer RNAs (tRNAs) they are essential for the translation of mRNA into an amino acid sequence.
Y1  - 2013
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/37140
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-371400
EP  - 118
PB  - Univ.-Bibliothek
CY  - Frankfurt am Main
ER  -