TY - JOUR A1 - Cabrera-Fuentes, Hector A. A1 - Alba-Alba, Corina A1 - Aragones, Julian A1 - Bernhagen, Jürgen A1 - Boisvert, William A. A1 - Bøtker, Hans E. A1 - Cesarman-Maus, Gabriela A1 - Fleming, Ingrid A1 - Garcia-Dorado, David A1 - Lecour, Sandrine A1 - Liehn, Elisa A1 - Marber, Michael S. A1 - Marina, Nephtali A1 - Mayr, Manuel A1 - Perez-Mendez, Oscar A1 - Miura, Tetsuji A1 - Ruiz-Meana, Marisol A1 - Salinas-Estefanon, Eduardo M. A1 - Ong, Sang-Bing A1 - Schnittler, Hans J. A1 - Sanchez-Vega, Jose T. A1 - Sumoza-Toledo, Adriana A1 - Vogel, Carl-Wilhelm A1 - Yarullina, Dina A1 - Yellon, Derek M. A1 - Preissner, Klaus T. A1 - Hausenloy, Derek J. T1 - Meeting report from the 2nd International Symposium on New Frontiers in Cardiovascular Research. Protecting the cardiovascular system from ischemia: between bench and bedside T2 - Basic research in cardiology N2 - Recent advances in basic cardiovascular research as well as their translation into the clinical situation were the focus at the last "New Frontiers in Cardiovascular Research meeting". Major topics included the characterization of new targets and procedures in cardioprotection, deciphering new players and inflammatory mechanisms in ischemic heart disease as well as uncovering microRNAs and other biomarkers as versatile and possibly causal factors in cardiovascular pathogenesis. Although a number of pathological situations such as ischemia-reperfusion injury or atherosclerosis can be simulated and manipulated in diverse animal models, also to challenge new drugs for intervention, patient studies are the ultimate litmus test to obtain unequivocal information about the validity of biomedical concepts and their application in the clinics. Thus, the open and bidirectional exchange between bench and bedside is crucial to advance the field of ischemic heart disease with a particular emphasis of understanding long-lasting approaches in cardioprotection. KW - Atherosclerosis KW - Cardioprotection KW - Cardiovascular disease KW - Endothelial permeability KW - Extracellular RNA KW - High-density lipoprotein KW - Hypoxia KW - Inflammation KW - Ischemia/reperfusion injury KW - Macrophage polarization KW - MicroRNAs KW - Mitochondria KW - Platelet dysfunction KW - Vascular biology Y1 - 2015 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/42738 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-427382 SN - 1435-1803 N1 - This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. VL - 111 IS - (1):7 SP - 1 EP - 13 PB - Springer CY - Berlin ; Heidelberg ER -