TY  - JOUR
A1  - Chandra, Prakash
A1  - Wacker, Adolf
T1  - Photodynamic effects on the template activity of nucleic acids
T2  - Zeitschrift für Naturforschung, B
N2  - The photodynamic inactivation of nucleic acids with pyronin, methylene blue, thiopyronin and furocoumarines has been studied. The template efficiency of DNA in RNA-Polymerase reaction was found to be decreased after the treatment of DNA with these compounds. However, the magnitude of their inhibiting capacity varied from one compound to the other. Psoralen and thiopyronin were found to be the most active inhibitors followed by xanthotoxin and methylene blue respectively. At a lower temperature the inhibiting capacity of thiopyronin was considerably decreased but that of psoralen remained nearly unaffected. We have also tried to show evidence for a complimentary code in t-RNA through a specific destruction of guanine with thiopyronin.
Y1  - 2014
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/71403
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-714030
SN  - 1865-7117
SN  - 0932-0776
VL  - 21
IS  - 7
SP  - 663
EP  - 666
PB  - Verlag der Zeitschrift für Naturforschung
CY  - Tübingen
ER  -