Prenatal ultrasound screening for fetal anomalies and outcomes in high-risk pregnancies due to maternal HIV infection : a retrospective study

  • Objective: To assess the prevalence of prenatal screening and of adverse outcome in high-risk pregnancies due to maternal HIV infection. Study design: The prevalence of prenatal screening in 330 pregnancies of HIV-positive women attending the department for prenatal screening and/or during labour between January 1, 2002 and December 31, 2012, was recorded. Screening results were compared with the postnatal outcome and maternal morbidity, and mother-to-child transmission (MTCT) was evaluated. Results: One hundred of 330 women (30.5%) had an early anomaly scan, 252 (74.5%) had a detailed scan at 20–22 weeks, 18 (5.5%) had a detailed scan prior to birth, and three (0.9%) had an amniocentesis. In seven cases (2.12%), a fetal anomaly was detected prenatally and confirmed postnatally, while in eight (2.42%) an anomaly was only detected postnatally, even though a prenatal scan was performed. There were no anomalies in the unscreened group. MTCT occurred in three cases (0.9%) and seven fetal and neonatal deaths (2.1%) were reported. Conclusion: The overall prevalence of prenatal ultrasound screening in our cohort is 74.5%, but often the opportunity for prenatal ultrasonography in the first trimester is missed. In general, the aim should be to offer prenatal ultrasonography in the first trimester in all pregnancies. This allows early reassurance or if fetal disease is suspected, further steps can be taken.

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Metadaten
Author:Anke Reitter, Anja-Undine Stücker, Horst Buxmann, Eva HerrmannORCiD, Annette Elisabeth Haberl, Rolf Lambert Schlößer, Frank Louwen
URN:urn:nbn:de:hebis:30:3-322747
DOI:https://doi.org/10.1155/2013/208482
ISSN:1098-0997
ISSN:1064-7449
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/24194633
Parent Title (English):Infectious diseases in obstetrics and gynecology
Publisher:Hindawi Publishing Corp.
Place of publication:New York, NY [u.a.]
Document Type:Article
Language:English
Date of Publication (online):2013/09/26
Date of first Publication:2013/09/26
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2013/11/08
Volume:2013
Issue:Article ID 208482
Page Number:11
First Page:1
Last Page:10
Note:
Copyright © 2013 A. Reitter et al. This is an open access article distributed under the Creative Commons Attribution License  http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
HeBIS-PPN:363137971
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 3.0