4 Ds in health research-working together toward rapid precision medicine

  • Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre-existing disease condition. Therapy remains predominantly symptom-based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine.

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Author:Ellen Niederberger, Michael J. Parnham, Jochen Maas, Gerd GeisslingerORCiDGND
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/31531943
Parent Title (English):EMBO molecular medicine
Publisher:Wiley-VCH ; EMBO Press
Place of publication:Weinheim ; Heidelberg
Document Type:Article
Year of Completion:2019
Date of first Publication:2019/09/18
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2020/05/04
Tag:Biomarkers & Diagnostic Imaging; Metabolism
Issue:11, e10917
Page Number:7
First Page:1
Last Page:7
© 2019 The Authors. Published under the terms of the CC BY 4.0 license.
Institutes:Biochemie, Chemie und Pharmazie / Pharmazie
Medizin / Medizin
Fachübergreifende Einrichtungen / Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 4.0