Ventral striatal activation during reward anticipation of different reward probabilities in adolescents and adults

  • Adolescence has been linked to an enhanced tolerance of uncertainty and risky behavior and is possibly connected to an increased response toward rewards. However, previous research has produced inconsistent findings. To investigate whether these findings are due to different reward probabilities used in the experimental design, we extended a monetary incentive delay (MID) task by including three different reward probabilities. Using functional magnetic resonance imaging, 25 healthy adolescents and 22 adults were studied during anticipation of rewards in the VS. Differently colored cue stimuli indicated either a monetary or verbal trial and symbolized different reward probabilities, to which the participants were blinded. Results demonstrated faster reaction times for lower reward probabilities (33%) in both age groups. Adolescents were slower through all conditions and had less activation on a neural level. Imaging results showed a three-way interaction between age group x condition x reward probability with differences in percent signal change between adolescents and adults for the high reward probabilities (66%, 88%) while adolescents demonstrated differences for the lowest (33%). Therefore, previous inconsistent findings could be due to different reward probabilities, which makes examining these crucial for a better understanding of adolescent and adult behavior.

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Author:Maria Bretzke, Hannes Wahl, Michael M. PlichtaORCiDGND, Nicole Wolff, Veit Rößner, Nora Vetter, Judith Buse
Parent Title (English):Frontiers in human neuroscience
Publisher:Frontiers Reserch Foundation
Place of publication:Lausanne
Document Type:Article
Date of Publication (online):2021/04/20
Date of first Publication:2021/04/20
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2021/09/29
Tag:adolescence; development; fMRI; reward; reward probabilities; ventral striatum
Issue:art. 649724
Page Number:13
First Page:1
Last Page:13
NV was funded by Deutsche Forschungsgemeinschaft, Grant/Award Numbers: VE 892/2-1. NW received funding from the Else-Kröner-Fresenius- Stiftung 2017_A101. The authors acknowledge support by the Open Access Publication Funds of the TU Dresden.
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 4.0