Patterns of care analysis for salivary gland cancer: a survey within the German Society of Radiation Oncology (DEGRO) and recommendations for daily practice

  • Background: Salivary gland cancer (SGC) is rare and a heterogeneous type of cancer. Prospective randomized trials are lacking. No guideline focusing on standard procedures of radiotherapy (RT) in the treatment of SGC exists. Therefore, we surveyed the members of the German Society of Radiation Oncology (DEGRO) to gain information about current therapeutic strategies of SGC. Methods: An anonymous questionnaire was designed and made available on the online platform The corresponding link was sent to all DEGRO members who provided their user data for contact purposes. Alternatively, a PDF printout version was sent. Frequency distributions of responses for each question were calculated. The data were also analyzed by type of institution. Results: Sixty-seven responses were received, including answers from 21 university departments, 22 non-university institutions, and 24 radiation oncology practices. Six participants reported that their departments (practice: n = 5, non-university hospital: n = 1) did not treat SGC, and therefore the questionnaire was not completed. Concerning radiation techniques, target volume definition, and concomitant chemotherapy, treatment strategies varied greatly among the participants. Comparing university vs. non-university institutions, university hospitals treat significantly more patients with SGC per year and initiated more molecular pathological diagnostics. Conclusion: SGC represents a major challenge for clinicians, as reflected by the inhomogeneous survey results regarding diagnostics, RT approaches, and systemic therapy. Future prospective, multicenter clinical trials are warranted to improve and homogenize treatment of SGC and to individualize treatment according to histologic subtypes and risk factors.
Author:Jens Müller-von der GrünORCiDGND, Claus RödelORCiDGND, Sabine SemrauORCiDGND, Panagiotis BalermpasORCiDGND, Daniel MartinORCiD, Rainer FietkauORCiDGND, Marlen P. HaderleinORCiDGND
Parent Title (German):Strahlentherapie und Onkologie
Publisher:Springer Medizin
Place of publication:Berlin; Heidelberg
Document Type:Article
Date of Publication (online):2021/08/24
Date of first Publication:2021/08/24
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2021/10/14
Tag:Molecular diagnostics; Radiotherapy; Salivary gland cancer; Stereotactic ablative body radiotherapy; Systemic therapy
Issue:Online Version before inclusion in an issue
Page Number:12
This work was supported by grants from the Else Kröner-Fresenius-Stiftung to Jens von der Grün. The authors did not receive support from any organization for the submitted work. Open Access funding enabled and organized by Projekt DEAL.
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Licence (German):License LogoCreative Commons - Namensnennung 4.0