SARS-CoV-2 asymptomatic and symptomatic patients and risk for transfusion transmission
- Oral swabs, sputum and blood samples from 18 patients with SARS-CoV-2 infection were examined using real-time reverse transcription polymerase chain reaction (RT-PCR) testing. Whereas oral swabs or sputum from the lower respiratory tract were tested RT-PCR positive in all patients, RNAemia was neither detected in 3 patients without symptoms nor in 14 patients with flu-like symptoms, fever or pneumonia. The only patient with RNAemia suffered from acute respiratory distress syndrome (ARDS) and was artificially ventilated in an intensive care unit. Risk for SARS-CoV-2 transmission through blood components in asymptomatic SARS-CoV-2 infected individuals therefore seems negligible but further studies are needed.
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| Author: | Victor Max CormanORCiDGND, Holger RabenauORCiDGND, Ortwin AdamsGND, Doris Franziska OberleORCiDGND, Markus B. FunkORCiDGND, Brigitte Keller-StanislawskiORCiDGND, Jörg TimmORCiDGND, Christian DrostenORCiDGND, Sandra CiesekORCiDGND |
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| URN: | urn:nbn:de:hebis:30:3-735497 |
| DOI: | https://doi.org/10.1101/2020.03.29.20039529 |
| Parent Title (English): | medRxiv |
| Document Type: | Preprint |
| Language: | English |
| Date of Publication (online): | 2020/05/30 |
| Date of first Publication: | 2020/05/30 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Release Date: | 2023/09/05 |
| Issue: | 2020.03.29.20039529 |
| Page Number: | 8 |
| HeBIS-PPN: | 511544103 |
| Institutes: | Medizin |
| Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Creative Commons - CC BY-ND - Namensnennung - Keine Bearbeitungen 4.0 International |
