Peak knee joint moments accurately predict medial and lateral knee contact forces in patients with valgus malalignment
- Compressive knee joint contact force during walking is thought to be related to initiation and progression of knee osteoarthritis. However, joint loading is often evaluated with surrogate measures, like the external knee adduction moment, due to the complexity of computing joint contact forces. Statistical models have shown promising correlations between medial knee joint contact forces and knee adduction moments in particularly in individuals with knee osteoarthritis or after total knee replacements (R2 = 0.44–0.60). The purpose of this study was to evaluate how accurately model-based predictions of peak medial and lateral knee joint contact forces during walking could be estimated by linear mixed-effects models including joint moments for children and adolescents with and without valgus malalignment. Peak knee joint moments were strongly correlated (R2 > 0.85, p < 0.001) with both peak medial and lateral knee joint contact forces. The knee flexion and adduction moments were significant covariates in the models, strengthening the understanding of the statistical relationship between both moments and medial and lateral knee joint contact forces. In the future, these models could be used to evaluate peak knee joint contact forces from musculoskeletal simulations using peak joint moments from motion capture software, obviating the need for time-consuming musculoskeletal simulations.
Author: | Jana HolderORCiDGND, Stefan van DrongelenORCiDGND, Scott David UhlrichORCiD, Eva HerrmannORCiDGND, Andrea MeurerORCiD, Felix StiefORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-826362 |
DOI: | https://doi.org/10.1038/s41598-023-30058-4 |
ISSN: | 2045-2322 |
Parent Title (English): | Scientific reports |
Publisher: | Macmillan Publishers Limited, part of Springer Nature |
Place of publication: | London |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2023/02/18 |
Date of first Publication: | 2023/02/18 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2024/05/14 |
Volume: | 13 |
Issue: | Article number: 2870 |
Article Number: | 2870 |
Page Number: | 11 |
Note: | Gefördert durch den Open-Access-Publikationsfonds der Goethe-Universität |
Institutes: | Medizin |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Open-Access-Publikationsfonds: | Medizin |
Licence (German): | ![]() |